Solitary and multiple thyroid nodules as predictors of malignancy: a systematic review and meta-analysis.

ABSTRACT:

Background

The debate on whether or not there is a difference in the incidence of thyroid cancer between the patients with Solitary thyroid Nodule (STN) and Multinodular Goiter (MNG) has been constantly present for the last few decades. With newer studies yielding mixed results, it was imperative to systematically compile all available literature on the topic.

Methods

PubMed/MEDLINE, Cochrane Central, ScienceDirect, GoogleScholar, International Clinical Trials registry, and reference lists of the included articles were systematically searched for article retrieval. No filter was applied in terms of time, study design, language or country of publication. Rigorous screening as per PRISMA guidelines was undertaken by 2 independent reviewers in order to identify the articles tha

SUBMITTER: Rehman AU 

PROVIDER: S-EPMC9720983 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature