The association of biomarkers with pain and function in acute and subacute low back pain: a secondary analysis of an RCT.

ABSTRACT:

Background

Low back pain (LBP) is a common musculoskeletal condition and a major cause of disability worldwide. Previous studies have found associations of biomarkers with pain and pain-related disability in LBP patients. This study aimed to explore the association between serum biomarkers and pain and disability in patients with acute or subacute axial LBP.

Methods

This study was ancillary to a parent randomized controlled trial. Enrolled participants were randomized into three intervention groups: one of two types of spinal manipulation or medical care. In the parent study, 107 adults who experienced a new episode of LBP within 3 months prior to enrollment were recruited. For this study, 90 of these 107 participants consented to have blood samples obtained, which were draw

SUBMITTER: Tonelli Enrico V 

PROVIDER: S-EPMC9721012 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature