Genomic landscape of prominent XDR Acinetobacter clonal complexes from Dhaka, Bangladesh.

ABSTRACT:

Background

Acinetobacter calcoaceticus-A. baumannii (ACB) complex pathogens are known for their prevalence in nosocomial infections and extensive antimicrobial resistance (AMR) capabilities. While genomic studies worldwide have elucidated the genetic context of antibiotic resistance in major international clones (ICs) of clinical Acinetobacter spp., not much information is available from Bangladesh. In this study, we analysed the AMR profiles of 63 ACB complex strains collected from Dhaka, Bangladesh. Following this, we generated draft genomes of 15 of these strains to understand the prevalence and genomic environments of AMR, virulence and mobilization associated genes in different Acinetobacter clones.

Results

Around 84% (n = 53) of the strains were extensively drug resist

SUBMITTER: Rahman A 

PROVIDER: S-EPMC9721023 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature