Dietary calcium and magnesium intake and risk for incident dementia: The Shanghai Aging Study.

ABSTRACT:

Introduction

Calcium (Ca), magnesium (Mg), or the calcium to magnesium (Ca:Mg) ratio may affect the risk of dementia via complex mechanisms. The aim of this study was to evaluate the association of dietary Ca, Mg, and Ca:Mg ratio with dementia risk at the prospective phase of the Shanghai Aging Study.

Methods

We analyzed data from 1565 dementia-free participants living in an urban community who had measurements of dietary Ca and Mg intake derived from a food frequency questionnaire at baseline and incident dementia during follow-up.

Results

Over the 5-year follow-up, 162 (10.4%) participants were diagnosed with incident dementia by Diagnostic and Statistical Manual of Mental Disorders, 4th edition criteria. Participants with the lowest tertile of dietary Ca (<339.1 mg

SUBMITTER: Luo J 

PROVIDER: S-EPMC9721293 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature