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Small-angle X-ray microdiffraction from fibrils embedded in tissue thin sections.


ABSTRACT: Small-angle X-ray scattering (SAXS) from fibrils embedded in a fixed, thin section of tissue includes contributions from the fibrils, the polymeric matrix surrounding the fibrils, other constituents of the tissue, and cross-terms due to the spatial correlation between fibrils and neighboring molecules. This complex mixture severely limits the amount of information that can be extracted from scattering studies. However, availability of micro- and nano-beams has made the measurement of scattering from very small volumes possible, which, in some cases, may be dominated by a single fibrillar constituent. In such cases, information about the predominant species may be accessible. Nevertheless, even in these cases, the correlations between the positions of fibrils and other constituents have a s

SUBMITTER: Nepal P 

PROVIDER: S-EPMC9721334 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature