Non-invasive cervical vagus nerve stimulation effects on reaction time and valence image anticipation response.

ABSTRACT:

Background

Norepinephrine (NE) driven noninvasive vagus nerve stimulation (nVNS), which improves attention and reduces reaction time, augments learning. Equally important, endogenous NE mediated arousal is highly dependent on the valence (positive or negative) of the exogenous stimulus. But to date, no study has measured valence specific effects of nVNS on both functional magnetic resonance imaging (fMRI) anticipation task response and reaction time in healthy individuals. Therefore, the aim of this pilot study was to assess whether nVNS vs sham modulates valence cortical anticipation task response and reaction time in a normative sample.

Methods

Participants received right sided transcutaneous cervical nVNS (N = 12) or sham (N = 12) stimulation during a 3T fMRI scan. Subjec

SUBMITTER: Lerman I 

PROVIDER: S-EPMC9721369 | biostudies-literature | 2022 Jul-Aug

REPOSITORIES: biostudies-literature