Whole brain correlates of individual differences in skin conductance responses during discriminative fear conditioning to social cues.

ABSTRACT: Understanding the neural basis for individual differences in the skin conductance response (SCR) during discriminative fear conditioning may inform on our understanding of autonomic regulation in fear-related psychopathology. Previous region-of-interest (ROI) analyses have implicated the amygdala in regulating conditioned SCR, but whole brain analyses are lacking. This study examined correlations between individual differences in SCR during discriminative fear conditioning to social stimuli and neural activity throughout the brain, by using data from a large functional magnetic resonance imaging study of twins (N = 285 individuals). Results show that conditioned SCR correlates with activity in the dorsal anterior cingulate cortex/anterior midcingulate cortex, anterior insula, bilate

SUBMITTER: Vinberg K 

PROVIDER: S-EPMC9721615 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature