Dysnatremias, Mortality, and Kidney Failure in CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study.

ABSTRACT:

Rationale & objective

Dysnatremias have been associated with an increased risk of mortality in the chronic kidney disease (CKD) population. Our objective is to identify the prevalence of and risk factors associated with dysnatremias in a CKD population and assess the association of dysnatremias with kidney failure and mortality among patients with CKD enrolled in the Chronic Renal Insufficiency Cohort Study.

Study design

Analysis of prospective cohort study.

Setting & participants

Adult patients aged 21-74 years with CKD from the Chronic Renal Insufficiency Cohort study.

Predictors

Baseline and time-dependent hyponatremia and hypernatremia.

Outcomes

All-cause mortality and kidney failure.

Analytical approach

Baseline characteristics were compared

SUBMITTER: Hassanein M 

PROVIDER: S-EPMC9722469 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature