Surgical management of severe pancreatic fistula after pancreatoduodenectomy: a comparison of early versus late rescue pancreatectomy.

ABSTRACT:

Background

Rescue pancreatectomy for postoperative pancreatic fistula (POPF) after pancreatoduodenectomy (PD) is associated with high mortality. However, in-depth literature is scarce and hard to interpret. This study aimed to evaluate the indications, timing and perioperative outcomes of rescue pancreatectomy for severe POPF after PD.

Methods

Retrospective single-centre study from all consecutive patients (2008-2020) with POPF-C after PD (ISGPS 2016 definition). Major morbidity and mortality during hospitalization or within 90 days after index surgery were evaluated. Time from index surgery to rescue pancreatectomy was dichotomized in early and late (≤ 11 versus > 11 days).

Results

From 1076 PDs performed, POPF-B/C occurred in 190 patients (17.7%) of whom 53 patients

SUBMITTER: Stoop TF 

PROVIDER: S-EPMC9722879 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature