Day of trophectoderm biopsy and embryo quality are associated with outcomes following euploid embryo transfer.

ABSTRACT:

Purpose

To compare clinical outcomes following transfer of euploid blastocysts of varying quality biopsied on day 5 versus day 6.

Methods

Retrospective cohort study to evaluate embryo transfer outcomes for women undergoing autologous cryopreserved next generation sequencing euploid single embryo transfer from 10/2015 to 2/2022 at an academic IVF program. The primary outcome was live birth rate (LBR). Secondary outcomes included ongoing pregnancy rate (OPR), implantation rate (IR), and miscarriage rate (SAB rate).

Results

Five hundred and fifty-five transfers from 418 patients were analyzed. Euploid embryos biopsied on day 5 resulted in higher LBR compared to those biopsied on day 6 (62.3% vs. 49.6%; aRR 0.81 95% CI 0.65-0.996). When stratified by biopsy day and blasto

SUBMITTER: Gordon CE 

PROVIDER: S-EPMC9723086 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature