Gut microbiota profile of COVID-19 patients: Prognosis and risk stratification (MicroCOVID-19 study).

ABSTRACT:

Background

Gut microbiota is intrinsically associated with the immune system and can promote or suppress infectious diseases, especially viral infections. This study aims to characterize and compare the microbiota profile of infected patients with SARS-CoV-2 (milder or severe symptoms), non-infected people, and recovered patients. This is a national, transversal, observational, multicenter, and case-control study that analyzed the microbiota of COVID-19 patients with mild or severe symptoms at home, at the hospital, or in the intensive care unit, patients already recovered, and healthy volunteers cohabiting with COVID-19 patients. DNA was isolated from stool samples and sequenced in a NGS platform. A demographic questionnaire was also applied. Statistical analysis was performed in

SUBMITTER: Nobre JG 

PROVIDER: S-EPMC9723140 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature