Fasting Glucose Variability and the Risk of Dementia in Individuals with Diabetes: A Nationwide Cohort Study.

ABSTRACT:

Background

We investigated whether fasting glucose (FG) variability could predict the risk of dementia.

Methods

This cohort study analyzed data from Koreans with diabetes after at least three health examinations by the Korean National Health Insurance Corporation between 2005 and 2010, which included at least one examination between 2009 and 2010. A total of 769,554 individuals were included, excluding those aged <40 years and those with dementia. FG variability was measured using the variability independent of the mean (FG-VIM). The incidence of dementia was defined by the International Classification of Diseases 10th Revision codes and prescription of anti-dementia medication and was subdivided into Alzheimer's disease (AD) and vascular dementia (VD).

Results

During

SUBMITTER: Lee DY 

PROVIDER: S-EPMC9723200 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature