Preterm Brain Injury and Neurodevelopmental Outcomes: A Meta-analysis.

ABSTRACT:

Context

Preterm brain injuries are common; neurodevelopmental outcomes following contemporary neonatal care are continually evolving.

Objective

To systematically review and meta-analyze neurodevelopmental outcomes among preterm infants after intraventricular hemorrhage (IVH) and white matter injury (WMI).

Data sources

Published and grey literature were searched across 10 databases between 2000 and 2021.

Study selection

Observational studies reporting 3-year neurodevelopmental outcomes for preterm infants with IVH or WMI compared with preterm infants without injury.

Data extraction

Study characteristics, population characteristics, and outcome data were extracted.

Results

Thirty eight studies were included. There was an increased adjusted risk of m

SUBMITTER: Rees P 

PROVIDER: S-EPMC9724175 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature