Risk factors for hospital-acquired infection during the SARS-CoV-2 pandemic.

ABSTRACT:

Objective

To evaluate risk factors for hospital-acquired infection (HAI) in patients during the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic, including historical and concurrent cohorts.

Design

Retrospective cohort.

Setting

Three Missouri hospitals, data from 1^st January 2017 to 30^th September 2020.

Participants

Patients aged ≥18 years and admitted for ≥48 h.

Methods

Univariate and multi-variate Cox proportional hazards models incorporating the competing risk of death were used to determine risk factors for HAI. A-priori sensitivity analyses were performed to assess the robustness of the urine-, blood- and respiratory-culture-based HAI definition.

Results

The cohort included 254,792 admissions, with 7

SUBMITTER: Kwon JH 

PROVIDER: S-EPMC9724556 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature