Reproducibility of quantitative flow ratio: the QREP study.

ABSTRACT:

Background

Quantitative flow ratio (QFR) is a tool for physiological lesion assessment based on invasive coronary angiography.

Aims

We aimed to assess the reproducibility of QFR computed from the same angiograms as assessed by multiple observers from different, international sites.

Methods

We included 50 patients previously enrolled in dedicated QFR studies. QFR was computed twice, one month apart by five blinded observers. The main analysis was the coefficient of variation (CV) as a measure of intra- and inter-observer reproducibility. Key secondary analysis was the identification of clinical and procedural characteristics predicting reproducibility.

Results

The intra-observer CV ranged from 2.3% (1.5-2.8) to 10.2% (6.6-12.0) among the observers. The inter-obs

SUBMITTER: Westra J 

PROVIDER: S-EPMC9724855 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature