Dataset Information

Optical coherence tomography to guide percutaneous coronary intervention of the left main coronary artery: the LEMON study.

ABSTRACT:

Background

Intravascular ultrasound (IVUS)-guided PCI improves the prognosis of left main stem (LMS) PCI and is currently recommended by international guidelines. Although OCT resolution is greater than that of IVUS, this tool is not yet recommended in LMS angioplasty due to the absence of data.

Aims

This pilot study aimed to analyse the feasibility, safety and impact of OCT-guided LMS PCI.

Methods

This prospective, multicentre trial investigated whether patients might benefit from OCT-guided PCI for mid/distal LMS according to a pre-specified protocol. The primary endpoint was procedural success defined as follows: residual angiographic stenosis <50% + TIMI 3 flow in all branches + adequate OCT stent expansion (LEMON criteria).