Geographical variations in left main coronary artery revascularisation: a prespecified analysis of the EXCEL trial.

ABSTRACT:

Background

The EXCEL trial reported similar five-year rates of the primary composite outcome of death, myocardial infarction (MI), or stroke after percutaneous coronary intervention (PCI) compared with coronary artery bypass grafting (CABG) for treatment of obstructive left main coronary artery disease (LMCAD).

Aims

We sought to determine whether these outcomes remained consistent regardless of geography of enrolment.

Methods

We performed a prespecified subgroup analysis based on regional enrolment.

Results

Among 1,905 patients randomised to PCI (n=948) or CABG (n=957), 1,075 (56.4%) were recruited at 52 European Union (EU) centres, and 752 (39.5%) were recruited at 67 North American (NA) centres. EU versus NA patients varied according to numerous baseline demo

SUBMITTER: Myat A 

PROVIDER: S-EPMC9724945 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature