Mortality after bleeding versus myocardial infarction in coronary artery disease: a systematic review and meta-analysis.

ABSTRACT:

Background

Bleeding is the principal safety concern of antithrombotic therapy and occurs frequently among patients with coronary artery disease (CAD).

Aims

We aimed to evaluate the prognostic impact of bleeding on mortality compared with that of myocardial infarction (MI) in patients with CAD.

Methods

We searched Medline and Embase for studies that included patients with CAD and that reported both the association between the occurrence of bleeding and mortality, and between the occurrence of MI and mortality within the same population. Adjusted hazard ratios (HRs) for mortality associated with bleeding and MI were extracted and ratios of hazard ratios (rHRs) were pooled by using inverse variance weighted random effects meta-analyses. Early events included periprocedur

SUBMITTER: Piccolo R 

PROVIDER: S-EPMC9725060 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature