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Recent Advances in Pediatric Cancer Research.


ABSTRACT: Over the past few years, the field of pediatric cancer has experienced a shift in momentum, and this has led to new and exciting findings that have relevance beyond pediatric malignancies. Here we present the current status of key aspects of pediatric cancer research. We have focused on genetic and epigenetic drivers of disease, cellular origins of different pediatric cancers, disease models, the tumor microenvironment, and cellular immunotherapies.

SUBMITTER: McEachron TA 

PROVIDER: S-EPMC9725930 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature

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Recent Advances in Pediatric Cancer Research.

McEachron Troy A TA   Helman Lee J LJ  

Cancer research 20210924 23


Over the past few years, the field of pediatric cancer has experienced a shift in momentum, and this has led to new and exciting findings that have relevance beyond pediatric malignancies. Here we present the current status of key aspects of pediatric cancer research. We have focused on genetic and epigenetic drivers of disease, cellular origins of different pediatric cancers, disease models, the tumor microenvironment, and cellular immunotherapies. ...[more]

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