Increased carbapenemase testing following implementation of national VA guidelines for carbapenem-resistant Enterobacterales (CRE).

ABSTRACT:

Objective

To describe national trends in testing and detection of carbapenemases produced by carbapenem-resistant Enterobacterales (CRE) and associate testing with culture and facility characteristics.

Design

Retrospective cohort study.

Setting

Department of Veterans' Affairs medical centers (VAMCs).

Participants

Patients seen at VAMCs between 2013 and 2018 with cultures positive for CRE, defined by national VA guidelines.

Interventions

Microbiology and clinical data were extracted from national VA data sets. Carbapenemase testing was summarized using descriptive statistics. Characteristics associated with carbapenemase testing were assessed with bivariate analyses.

Results

Of 5,778 standard cultures that grew CRE, 1,905 (33.0%) had evidence of mo

SUBMITTER: Fitzpatrick MA 

PROVIDER: S-EPMC9726513 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature