Muscle mass loss is associated with physical dysfunction in patients with early rheumatoid arthritis.

ABSTRACT:

Background

Muscle mass loss is common in long-standing rheumatoid arthritis (RA). The aim was to explore the prevalence and effects of RA disease characteristics in patients with early RA.

Methods

This cross-sectional study was carried out based on a Chinese RA cohort and control subjects. The body composition (BC) was assessed using bioelectric impedance analysis. Myopenia was defined by an appendicular skeletal muscle mass index of ≤ 7.0 kg/m² in men and ≤ 5.7 kg/m² in women. Physical dysfunction was defined as a health assessment questionnaire disability index > 1. Propensity score matching was performed to balance age and gender differences among patients with early RA (disease duration ≤ 12 months) and established RA, and controls (with 1:3:3 match

SUBMITTER: Pan J 

PROVIDER: S-EPMC9727302 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature