Efficacy of awake prone positioning in patients with covid-19 related hypoxemic respiratory failure: systematic review and meta-analysis of randomized trials.

ABSTRACT:

Objective

To determine the efficacy and safety of awake prone positioning versus usual care in non-intubated adults with hypoxemic respiratory failure due to covid-19.

Design

Systematic review with frequentist and bayesian meta-analyses.

Study eligibility

Randomized trials comparing awake prone positioning versus usual care in adults with covid-19 related hypoxemic respiratory failure. Information sources were Medline, Embase, and the Cochrane Central Register of Controlled Trials from inception to 4 March 2022.

Data extraction and synthesis

Two reviewers independently extracted data and assessed risk of bias. Random effects meta-analyses were performed for the primary and secondary outcomes. Bayesian meta-analyses were performed for endotracheal intubation and

SUBMITTER: Weatherald J 

PROVIDER: S-EPMC9727649 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature