Quality of observational studies of clinical interventions: a meta-epidemiological review.

ABSTRACT:

Background

This meta-epidemiological study aimed to assess methodological quality of a sample of contemporary non-randomised clinical studies of clinical interventions.

Methods

This was a cross-sectional study of observational studies published between January 1, 2012 and December 31, 2018. Studies were identified in PubMed using search terms 'association', 'observational,' 'non-randomised' 'comparative effectiveness' within titles or abstracts. Each study was appraised against 35 quality criteria by two authors independently, with each criterion rated fully, partially or not satisfied. These quality criteria were grouped into 6 categories: justification for observational design (n = 2); minimisation of bias in study design and data collection (n = 11); use of appropriate me

SUBMITTER: Grosman S 

PROVIDER: S-EPMC9727931 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature