Is Greenness Associated with Dementia? A Systematic Review and Dose-Response Meta-analysis.
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ABSTRACT: Purpose of review
We assessed the relation between environmental greenness and risk of dementia and cognitive impairment, based on a systematic review and meta-analysis up to March 30, 2022, characterizing whenever possible the shape of the association using dose-response meta-analysis.Recent findings
Twelve studies were included in this review, either using normalized difference vegetation index (NDVI) or land use/cover (LU/LC) methodology to assess greenness. Comparing the highest versus lowest exposure categories of greenness assessed using the NDVI (6 studies) or LU/LC (6 studies), we found no association with dementia. Dose-response meta-analysis of the association between greenness measured by LU/LC and dementia, based on only 3 studies, indicated a U-shaped association, but estimates were imprecise. Our systematic review and meta-analysis provided some evidence of a slight inverse association between greenness and dementia at intermediate exposure levels, but not at high levels. Potential methodological limitations, such as exposure misclassification and unmeasured confounding, may have affected the results.
SUBMITTER: Zagnoli F
PROVIDER: S-EPMC9729322 | biostudies-literature | 2022 Dec
REPOSITORIES: biostudies-literature
Publications
Is Greenness Associated with Dementia? A Systematic Review and Dose-Response Meta-analysis.
Zagnoli Federico F Filippini Tommaso T Jimenez Marcia P MP Wise Lauren A LA Hatch Elizabeth E EE Vinceti Marco M
Current environmental health reports 20220720 4
<h4>Purpose of review</h4>We assessed the relation between environmental greenness and risk of dementia and cognitive impairment, based on a systematic review and meta-analysis up to March 30, 2022, characterizing whenever possible the shape of the association using dose-response meta-analysis.<h4>Recent findings</h4>Twelve studies were included in this review, either using normalized difference vegetation index (NDVI) or land use/cover (LU/LC) methodology to assess greenness. Comparing the high ...[more]
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