Experimentally induced myopia and myopic astigmatism alter retinal electrophysiology in chickens.

ABSTRACT: Myopia (or "short-sightedness") and astigmatism are major causes of visual impairment worldwide. Significant amounts of astigmatism are frequently observed in infants and have been associated with myopia development. Although it is well established that both myopia and astigmatism are associated with ocular structural changes from anterior to posterior segments, very little is known on how these refractive errors alter retinal functions. This study investigated the effects of experimentally induced myopia and myopic-astigmatism on retinal electrophysiology by using an image-guided, multifocal global flash stimulation in chickens, a widely used animal model for refractive error development. Myopia and myopic-astigmatism were experimentally induced, respectively, by wearing spherical (- 10 D

SUBMITTER: Vyas SA 

PROVIDER: S-EPMC9729572 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature