Multi-trajectories of systolic and diastolic hypertension and coronary heart disease in middle-aged and older adults.

ABSTRACT:

Objective

This study aimed to investigate multi-trajectories of systolic and diastolic hypertension and assess their association with the risk of coronary heart disease (CHD) in middle-aged and older Chinese adults.

Methods

The study cohort comprised 4,102 individuals aged 40-75 years with records of at least four systolic blood pressure (SBP) and diastolic blood pressure (DBP). A group-based multi-trajectory model was adopted to identify multi-trajectories of systolic and diastolic hypertension, followed by a logistic model to assess the independent associations between these trajectories and CHD risk. The multinomial logistic model was used to evaluate the impact of baseline covariates on trajectory groups.

Results

Six distinct trajectories for systolic and diastoli

SUBMITTER: Li M 

PROVIDER: S-EPMC9729777 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature