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Mo@ZIF-8 nanozyme preparation and its antibacterial property evaluation.

ABSTRACT: Types of nanozymes can produce free radicals and/or reactive oxygen species (ROS) to serve as broad spectrum antibacterial materials. Developing nanozyme-based antibacterial materials with good biocompatibility exhibits promising application prospects. In this study, we doped Mo to ZIF-8 (both components have good biocompatibility) to prepare a new nanozyme, Mo@ZIF-8, which can produce hydroxyl radicals (•OH) triggered by a low dosage of hydrogen peroxide (H₂O₂), exhibiting effective antibacterial capability against both Gram-negative bacteria (Escherichia coli) and Gram-positive bacteria (Staphylococcus aureus). This work provides a reference for the design of antibacterial nanozymes with good biocompatibility.

SUBMITTER: Lian Z

PROVIDER: S-EPMC9730516 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature

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Mo@ZIF-8 nanozyme preparation and its antibacterial property evaluation.

Lian Zheng Z Lu Chunqing C Zhu Jiangqi J Zhang Xining X Wu Ting T Xiong Youlin Y Sun Zhiyi Z Yang Rong R

Frontiers in chemistry 20221124

Types of nanozymes can produce free radicals and/or reactive oxygen species (ROS) to serve as broad spectrum antibacterial materials. Developing nanozyme-based antibacterial materials with good biocompatibility exhibits promising application prospects. In this study, we doped Mo to ZIF-8 (both components have good biocompatibility) to prepare a new nanozyme, Mo@ZIF-8, which can produce hydroxyl radicals (•OH) triggered by a low dosage of hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>), exhibiting ...[more]

PMID: 36505748

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