Brain white matter hyperintensity lesion characterization in 3D T₂ fluid-attenuated inversion recovery magnetic resonance images: Shape, texture, and their correlations with potential growth.

ABSTRACT: Analyses of age-related white matter hyperintensity (WMH) lesions manifested in T₂ fluid-attenuated inversion recovery (FLAIR) magnetic resonance images (MRI) have been mostly on understanding the size and location of the WMH lesions and rarely on the morphological characterization of the lesions. This work extends our prior analyses of the morphological characteristics and texture of WMH from 2D to 3D based on 3D T₂ FLAIR images. 3D Zernike transformation was used to characterize WMH shape; a fuzzy logic method was used to characterize the lesion texture. We then clustered 3D WMH lesions into groups based on their 3D shape and texture features. A potential growth index (PGI) to assess dynamic changes in WMH lesions was developed based on the image texture features of

SUBMITTER: Gwo CY 

PROVIDER: S-EPMC9731131 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature