Non-linear association of birth weight with lung function and risk of asthma: A population-based study

ABSTRACT:

Background

The impact of birth weight on lung function and risk of asthma remains contentious. Our aim was to investigate the specific association of birth weight with lung function and the risk of asthma in children.

Methods

We performed cross-sectional analyses of 3,295 children aged 6–15 years who participated in the 2007–2012 National Health and Nutrition Examination Survey (NHANES). After controlling for potential covariates other than gestational diabetes, maternal asthma and obesity, the linear and non-linear associations of birth weight with lung function metrics and the risk of asthma were evaluated by a generalized linear model and generalized additive model, respectively.

Results

We observed a non-linear association of birth weight with FEV1 %predicted

SUBMITTER: Yang M 

PROVIDER: S-EPMC9731215 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature