Neuroimaging in Pediatric Patients with Juvenile Xanthogranuloma of the CNS.

ABSTRACT:

Background and purpose

Juvenile xanthogranuloma is a rare clonal, myeloid, neoplastic disorder. Typically, juvenile xanthogranuloma is a self-limited disorder of infancy, often presenting as a solitary red-brown or yellow skin papule/nodule. A small subset of patients present with extracutaneous, systemic juvenile xanthogranuloma, which may include the CNS. The goal of this retrospective study was to evaluate and categorize the neuroimaging findings in a representative cohort of pediatric patients with CNS juvenile xanthogranuloma.

Materials and methods

The brain and/or spine MR imaging data of 14 pediatric patients with pathology-proven juvenile xanthogranuloma were categorized and evaluated for the location; the signal intensity of xanthogranulomas on T1WI, T2WI, DWI, and

SUBMITTER: Serrallach BL 

PROVIDER: S-EPMC9731252 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature