Machine learning approach for hemorrhagic transformation prediction: Capturing predictors' interaction.

ABSTRACT:

Background and purpose

Patients with ischemic stroke frequently develop hemorrhagic transformation (HT), which could potentially worsen the prognosis. The objectives of the current study were to determine the incidence and predictors of HT, to evaluate predictor interaction, and to identify the optimal predicting models.

Methods

A prospective study included 360 patients with ischemic stroke, of whom 354 successfully continued the study. Patients were subjected to thorough general and neurological examination and T2 diffusion-weighted MRI, at admission and 1 week later to determine the incidence of HT. HT predictors were selected by a filter-based minimum redundancy maximum relevance (mRMR) algorithm independent of model performance. Several machine learning algorithms includ

SUBMITTER: Elsaid AF 

PROVIDER: S-EPMC9731336 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature