Neurological manifestations of scrub typhus infection: A systematic review and meta-analysis of clinical features and case fatality.

ABSTRACT:

Background

Scrub typhus has become a leading cause of central nervous system (CNS) infection in endemic regions. As a treatable condition, prompt recognition is vital. However, few studies have focused on describing the symptomology and outcomes of neurological scrub typhus infection. We conducted a systematic review and meta-analysis to report the clinical features and case fatality ratio (CFR) in patients with CNS scrub typhus infection.

Methods

A search and analysis plan was published in PROSPERO [ID 328732]. A systematic search of PubMed and Scopus was performed and studies describing patients with CNS manifestations of proven scrub typhus infection were included. The outcomes studied were weighted pooled prevalence (WPP) of clinical features during illness and weighted

SUBMITTER: Alam AM 

PROVIDER: S-EPMC9731453 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature