Effects of various treatments for preventing oral mucositis in cancer patients: A network meta-analysis

ABSTRACT:

Background

Oral mucositis (OM) is a common side effect of chemotherapy and radiotherapy in patients with cancers. The prevention or treatment of OM in cancer patients is crucial in the treatment of cancer.

Methods

We searched PubMed, Embase, and Cochrane Library for the randomized control trials (RCTs) of interventions for preventing and treating OM. Network meta-analysis (NMA) was performed to estimate odds ratios (ORs) and 95% confidence intervals (CI) from both direct and indirect evidence. The prespecified primary efficacy outcome was the treatment effect of moderate to severe oral mucositis with 12 interventions. The outcome was moderate to a severe grade of OM.

Results

This study included 55 RCTs with 3,552 participants. The results showed that honey signif

SUBMITTER: Peng T 

PROVIDER: S-EPMC9731456 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature