Catalytic direct hydrocarboxylation of styrenes with CO₂ and H₂.

ABSTRACT: A three-component hydrocarboxylation of an olefin with CO₂ and H₂ could be regarded as a dream reaction, since it would provide a straightforward approach for the synthesis of aliphatic carboxylic acids in perfect atom economy. However, this transformation has not been realized in a direct manner under mild conditions, because boosting the carboxylation with thermodynamically stable CO₂ while suppressing the rapid hydrogenation of olefin remains a challenging task. Here, we report a rhodium-catalysed reductive hydrocarboxylation of styrene derivatives with CO₂ and H₂ under mild conditions, in which H₂ served as the terminal reductant. In this approach, the carboxylation process was largely accelerated by visible light irradi

SUBMITTER: Jin Y 

PROVIDER: S-EPMC9732006 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature