Corticospinal neurons from motor and somatosensory cortices exhibit different temporal activity dynamics during motor learning.

ABSTRACT: The ability to learn motor skills implicates an improvement in accuracy, speed and consistency of movements. Motor control is related to movement execution and involves corticospinal neurons (CSp), which are broadly distributed in layer 5B of the motor and somatosensory cortices. CSp neurons innervate the spinal cord and are functionally diverse. However, whether CSp activity differs between different cortical areas throughout motor learning has been poorly explored. Given the importance and interaction between primary motor (M1) and somatosensory (S1) cortices related to movement, we examined the functional roles of CSp neurons in both areas. We induced the expression of GCaMP7s calcium indicator to perform photometric calcium recordings from layer 5B CSp neurons simultaneously in M1 and

SUBMITTER: Macias M 

PROVIDER: S-EPMC9732016 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature