Association between timing of intubation and mortality in patients with idiopathic pulmonary fibrosis.

ABSTRACT:

Background

Delayed intubation is associated with poor prognosis in patients with respiratory failure. However, the effect of delayed intubation in patients with idiopathic pulmonary fibrosis (IPF) remains unknown. This study aimed to analyze whether timing of intubation after high-concentration oxygen therapy was associated with worse clinical outcomes in IPF patients.

Methods

This retrospective propensity score-matched study enrolled adult patients with IPF who underwent mechanical ventilation between January 2011 and July 2021. Patients were divided into early and delayed intubation groups. Delayed intubation was defined as use of high-concentration oxygen therapy for at least 48 hours before tracheal intubation. The primary outcome was intensive care unit (ICU) mortality,

SUBMITTER: Bae E 

PROVIDER: S-EPMC9732203 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature