Early structural connectivity within the sensorimotor network: Deviations related to prematurity and association to neurodevelopmental outcome.

ABSTRACT: Consisting of distributed and interconnected structures that interact through cortico-cortical connections and cortico-subcortical loops, the sensorimotor (SM) network undergoes rapid maturation during the perinatal period and is thus particularly vulnerable to preterm birth. However, the impact of prematurity on the development and integrity of the emerging SM connections and their relationship to later motor and global impairments are still poorly understood. In this study we aimed to explore to which extent the early microstructural maturation of SM white matter (WM) connections at term-equivalent age (TEA) is modulated by prematurity and related with neurodevelopmental outcome at 18 months corrected age. We analyzed 118 diffusion MRI datasets from the developing Human Connectome Projec

SUBMITTER: Neumane S 

PROVIDER: S-EPMC9732267 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature