Ontology highlight
ABSTRACT:
SUBMITTER: Bergamini G
PROVIDER: S-EPMC9732550 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Bergamini Giorgio G Coloma Preciosa P Massinet Helene H Steiner Michel Alexander MA
Frontiers in psychiatry 20221125
Neuropsychiatric symptoms (NPS) affect people with dementia (PwD) almost universally across all stages of the disease, and regardless of its exact etiology. NPS lead to disability and reduced quality of life of PwD and their caregivers. NPS include hyperactivity (agitation and irritability), affective problems (anxiety and depression), psychosis (delusions and hallucinations), apathy, and sleep disturbances. Preclinical studies have shown that the orexin neuropeptide system modulates arousal and ...[more]