Sex-Specific Differences in Ventricular Remodeling and Response After Cardiac Resynchronization Therapy.

ABSTRACT: In this study, we investigated the baseline characteristics and "trajectories" of clinical response in men and women after cardiac resynchronization therapy (CRT) implantation. Although women enjoy improved echocardiographic response after CRT compared with men, the kinetics of this response and its relation to functional performance and outcomes are less clear. We identified 592 patients who underwent CRT implantation at our center between 2004 and 2017 and were serially followed in a multidisciplinary clinic. Longitudinal linear mixed effects regression for cardiac response was specified, including interaction terms between time after CRT and sex , and Cox regression models were used to assess differences in all-cause mortality by gender after CRT. Women in our cohort were younger than m

SUBMITTER: Varrias D 

PROVIDER: S-EPMC9732763 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature