PerBrain: a multimodal approach to personalized tracking of evolving state-of-consciousness in brain-injured patients: protocol of an international, multicentric, observational study.

ABSTRACT:

Background

Disorders of consciousness (DoC) are severe neurological conditions in which consciousness is impaired to various degrees. They are caused by injury or malfunction of neural systems regulating arousal and awareness. Over the last decades, major efforts in improving and individualizing diagnostic and prognostic accuracy for patients affected by DoC have been made, mainly focusing on introducing multimodal assessments to complement behavioral examination. The present EU-funded multicentric research project "PerBrain" is aimed at developing an individualized diagnostic hierarchical pathway guided by both behavior and multimodal neurodiagnostics for DoC patients.

Methods

In this project, each enrolled patient undergoes repetitive behavioral, clinical, and neurodiagnos

SUBMITTER: Willacker L 

PROVIDER: S-EPMC9733076 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature