Pro-MAP: a robust pipeline for the pre-processing of single channel protein microarray data.

ABSTRACT:

Background

The central role of proteins in diseases has made them increasingly attractive as therapeutic targets and indicators of cellular processes. Protein microarrays are emerging as an important means of characterising protein activity. Their accurate downstream analysis to produce biologically significant conclusions is largely dependent on proper pre-processing of extracted signal intensities. However, existing computational tools are not specifically tailored to the nature of these data and lack unanimity.

Results

Here, we present the single-channel Protein Microarray Analysis Pipeline, a tailored computational tool for analysis of single-channel protein microarrays enabling biomarker identification, implemented in R, and as an interactive web application. We compare

SUBMITTER: Mowoe MO 

PROVIDER: S-EPMC9733281 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature