Therapeutic Polypeptides and Peptidomimetics: Powerful Tools for COVID-19 Treatment.

ABSTRACT: The coronavirus disease 2019 (COVID-19) pandemic has swept the whole world and brought about a public health crisis of unprecedented proportions. To combat the rapid transmission and possible deaths due to the disease, researchers and companies around the world are developing all possible strategies. Due to the advantages of safety, specificity, and fewer adverse effects, polypeptide and peptidomimetic drugs are considered promising strategies. This review comprehensively summarizes and discusses the progress in development of peptide drugs for use in the treatment of COVID-19. Based on the latest results in this field, we divided them into clinically approved drugs, clinical trial drugs, and clinically ineffective drugs, and outlined the molecular targets and mechanisms of action one by o

SUBMITTER: Liu X 

PROVIDER: S-EPMC9734822 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature