Assessment and Distribution of Runs of Homozygosity in Horse Breeds Representing Different Utility Types.

ABSTRACT: The present study reports runs of homozygosity (ROH) distribution in the genomes of six horse breeds (571 horses in total) representing three horse types (primitive, light, and draft horses) based on the 65k Equine BeadChip assay. Of major interest was the length, quantity, and frequency of ROH characteristics, as well as differences between horse breeds and types. Noticeable differences in the number, length and distribution of ROH between breeds were observed, as well as in genomic inbreeding coefficients. We also identified regions of the genome characterized by high ROH coverage, known as ROH islands, which may be signals of recent selection events. Eight to fourteen ROH islands were identified per breed, which spanned multiple genes. Many were involved in important horse breed charact

SUBMITTER: Szmatola T 

PROVIDER: S-EPMC9736150 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature