A Disturbed Siderophore Transport Inhibits Myxobacterial Predation.

ABSTRACT: Understanding the intrinsic mechanisms of bacterial competition is a fundamental question. Iron is an essential trace nutrient that bacteria compete for. The most prevalent manner for iron scavenging is through the secretion of siderophores. Although tremendous efforts have focused on elucidating the molecular mechanisms of siderophores biosynthesis, export, uptake, and regulation of siderophores, the ecological aspects of siderophore-mediated competition are not well understood. We performed predation and bacterial competition assays to investigate the function of siderophore transport on myxobacterial predation. Deletion of msuB, which encodes an iron chelate uptake ABC transporter family permease subunit, led to a reduction in myxobacterial predation and intracellular iron, but iron def

SUBMITTER: Dong Y 

PROVIDER: S-EPMC9738627 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature