Hgtseq: A Standard Pipeline to Study Horizontal Gene Transfer.

ABSTRACT: Horizontal gene transfer (HGT) is well described in prokaryotes: it plays a crucial role in evolution, and has functional consequences in insects and plants. However, less is known about HGT in humans. Studies have reported bacterial integrations in cancer patients, and microbial sequences have been detected in data from well-known human sequencing projects. Few of the existing tools for investigating HGT are highly automated. Thanks to the adoption of Nextflow for life sciences workflows, and to the standards and best practices curated by communities such as nf-core, fully automated, portable, and scalable pipelines can now be developed. Here we present nf-core/hgtseq to facilitate the analysis of HGT from sequencing data in different organisms. We showcase its performance by analysing si

SUBMITTER: Carpanzano S 

PROVIDER: S-EPMC9738810 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature