How Should We Treat Meningeal Melanocytoma? A Retrospective Analysis of Potential Treatment Strategies.

ABSTRACT: Meningeal melanocytomas (MM) are rare primary melanocytic tumors of the leptomeninges with an incidence of 1:10,000,000. Until now, there has been only sparse information about this tumor entity. Here, we provide a meta-analysis of all cases published in the English language since 1972. A literature review was performed using PubMed and Web of Science. All published cases were evaluated for location, sex, age, therapeutic approach, and outcome. In total, we included 201 patient cases in our meta-analysis. The majority of MM was diagnosed more frequently in men between the third and fifth decade of life. Surgery is the preferred therapeutic approach, and total resection is associated with the best outcome. Patients with partial resection or tumor recurrence benefit from adjuvant radiotherap

SUBMITTER: Ricchizzi S 

PROVIDER: S-EPMC9738837 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature