Two-Component Systems of Streptomyces coelicolor: An Intricate Network to Be Unraveled.

ABSTRACT: Bacteria of the Streptomyces genus constitute an authentic biotech gold mine thanks to their ability to produce a myriad of compounds and enzymes of great interest at various clinical, agricultural, and industrial levels. Understanding the physiology of these organisms and revealing their regulatory mechanisms is essential for their manipulation and application. Two-component systems (TCSs) constitute the predominant signal transduction mechanism in prokaryotes, and can detect a multitude of external and internal stimuli and trigger the appropriate cellular responses for adapting to diverse environmental conditions. These global regulatory systems usually coordinate various biological processes for the maintenance of homeostasis and proper cell function. Here, we review the multiple

SUBMITTER: Sanchez de la Nieta R 

PROVIDER: S-EPMC9739842 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature