Populations of NK Cells and Regulatory T Cells in the Endometrium of Cycling Mares—A Preliminary Study

ABSTRACT:

Simple Summary

Endometrial immune cells, such as regulatory T cells and NK cells, are not well known in mares. Nevertheless, these cells play important roles both in physiological and pathological processes in equine reproduction. This work aimed to characterize populations of regulatory T cells and NK cells in the endometrium of cycling mares. With the use of specific antibodies, we showed that two different types of regulatory T cells and NK cells are present both during estrus and diestrus in mares.

Abstract

Endometrial immune cells are essential to support uterine functions across the estrous cycle and in preparation for pregnancy. It has been acknowledged that changes in phenotype and/or numbers of lymphocytes, such as regulatory T cells (Tregs) and NK cells, might r

SUBMITTER: Jaworska J 

PROVIDER: S-EPMC9740928 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature