Diagnostic Test Accuracy of Genetic Tests in Diagnosing Psoriasis: A Systematic Review.

ABSTRACT: The pathogenesis of psoriasis involves the interaction of several environmental and genetic factors. Predicting the disease risk cannot depend on individual genetic alleles. Consequently, some studies have evaluated the use of genetic risk scores that combine several psoriasis susceptibility loci to increase the accuracy of predicting/diagnosing the disease. This meta-analysis summarizes the evidence regarding using genetic risk scores (GRS) in the diagnosis or prediction of psoriasis. A search of MEDLINE/PubMed, the Latin American Caribbean Health Sciences Literature (LILACS) database, Cochrane Library, Scopus, Web of Science, and ProQuest was conducted in July 2022. The primary objective was to record the area under the curve (AUC) for GRS of psoriasis. Secondary objectives included char

SUBMITTER: Mirghani H 

PROVIDER: S-EPMC9741513 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature