Extremely Early-Onset Frontotemporal Dementia: A Case Report and Literature Review.

ABSTRACT:

Background

In most cases, the onset of frontotemporal dementia (FTD) occurs between the ages of 45 and 65 years. However, some patients experience an extremely early disease onset.

Objective

To investigate the clinical, genetic, and pathological features of extremely early-onset FTD.

Methods

We conducted a comprehensive clinical, genetic, and neuropathological analysis of a 25-year-old patient experiencing the onset of behavioral variant frontotemporal dementia (bvFTD). In addition, we conducted a literature review and summarized the clinical, genetic, and pathological features of patients with FTD with onset age≤25 years.

Results

The patient was diagnosed with bvFTD; however, there was no family history of FTD, no positive genetic test results and no depositio

SUBMITTER: Chu M 

PROVIDER: S-EPMC9741737 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature